Indevus currently sells treatments for overactive bladder, prostate cancer and central precociouspuberty.
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Objective: Children with precociouspuberty (PP) may have increased physiological and psychological problems.
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Younger patients had respiratory complaints; older patients had chest pain, precociouspuberty, or facial fullness.
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Other symptoms included behavioral abnormalities in four patients and precociouspuberty and visual impairment in two patients.
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But is precociouspuberty the new norm?
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The pediatrician's first reaction to then second-grader Kayla Haye's budding breasts- asignof the child's prematurepuberty-wasto consider placing her on therapeutic hormones.
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Often the manifestation of sexualprecocity is less gross, but almost equally fraught with danger, nevertheless.
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When the adrenals increase in size in childhood, a remarkable triad follows-generalhairiness, adiposity and sexualprecocity.
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Lesions of the hypothalamus that cause sexualprecocity transiently activate neuronal TTF-1 expression near the lesion site.
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Depression, anger, and, ah, sexualprecocity.
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Age at presentation was 12-17 years, except for one 7-year-old who presented with sexualprecocity.